Kontakt

Dr. Christa Trattnig

Gruppenleiterin


Anatomie und Zellbiologie
Im Neuenheimer Feld 307
69120 Heidelberg
Tel. 06221-548687
Fax 06221-544952
Email


Gruppe Trattnig

Research Summary

Physiological brain function depends crucially on the proper balance of inhibitory and excitatory neurotransmission through chemical synapses outnumbering the amount of nerve cells by a multiple (approximately 86 million nerve cells in contrast to an estimated number of 100 trillions of synapses).

 

Structural alterations of the specific molecular composition at synapses are thought to be implicated in plasticity, learning, memory formation and also in various diseases and injuries of the brain. We are keen to decipher the molecular composition and ultrastructure of inhibitory synapses with respect to the onset, formation and progression of brain injury and brain inflammation.


We stain inhibitory synapses with synapse specific antibodies and visualize them by high-resolution confocal microscopy (see picture below).

Inhibitory synapses (red dots: presynapse, green dots: postsynapse, blue: nuclei stain) in the dentate gyrus of the rat hippocampus

 

For further information and inquiries please contact:

 

Dr. Christa Trattnig

Ruprecht-Karls-Universität Heidelberg

Institut für Anatomie und Zellbiologie

Abt. Med. Zellbiologie

Im Neuenheimer Feld 307

D-69120 Heidelberg

+49 6221 54 8687

trattnig@ana.uni-heidelberg.de

 

Group Leader

Dr. Christa Trattnig

Group Members

Karin Rummer (Technical Assistant)




Verantwortlich: E-Mail,   Letzte Änderung: Tue, 11.09.2018
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