Jens Strelau


Anatomie und Zellbiologie
Im Neuenheimer Feld 307
69120 Heidelberg
Tel. 06221 54 8345
Fax: 06221 54 5604

Strelau group

Research summary

Signal transduction by neurotrophic factors

Neuroactive proteins and peptides play a key role both in nervous system homoeostasis and in pathological processes like inflammation, neurodegeneration and tumorigenesis. Our group is particularly interested in deciphering the function of growth differentiation factor-15 (GDF-15), a member of the transforming growth factor-beta superfamily during embryonic development and in the normal or lesioned adult nervous system. Our approach involves the generation and analysis of transgenic mouse models, tissue and (primary cell) cultures combined with state-of-the-art molecular biology methods and complemented by newest imaging techniques.



DFG research grant “CPNF a novel member of the TGF-ß superfamily” (Str 616/1-2, 2000-2003). DFG research grant “GDF-15 in the developing CNS” (Str 616/3-4, 2004-2007). DFG research grant “Functions of GDF-15 in neuron survival and peripheral myelination” (UN 34/23-1, 2007-20011). DFG research grant “The role of GDF-15 in the progression of atherosclerosis” (KI 695/6-1, 2009-2013).


Group Leader
Dr. Jens Strelau


Goup Members

Gerald Bendner
Richard Hertel
Anna Steinmann









Verantwortlich: E-Mail,   Letzte Änderung: Mon, 25.11.2019
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